The HER2 receptor is a 195-kDa transmembrane glycoprotein with tyrosine kinase activity, and belongs in the human epidermal growth factor receptor (HER) family consisting of four members. Moreover, aberrant HER2 protein over-expression has been linked to various human gynaecological adenocarcinomas, including breast, endometrium, ovary and cervix, and has been found to be a poor prognostic factor for survival. This new book presents topical research in the study of HER2, including targeting HER2 with photodynamic therapy; HER2 shedding as a biomarker in breast cancer; development of trastuzumab resistance and targeted nanomedicines conjugated with HER2 antibodies in cancer therapy.
|Use of Ecological Indices to Detect Changes in Ecosystem Health Following Restoration Efforts in Cootes Paradise Marsh|
|Changes in Fish Communities of Lake Ontario Coastal Wetlands Before & After Remedial Action Plans|
|Use of Ecological Indicators to Assess the Quality of Great Lakes Coastal Wetlands|
|Development of an Inventory of Coastal Wetlands for Eastern Georgian Bay, Lake Huron|
|Great Lakes: Form & Function, as Exemplified using Data from Lake Vñnern, the Fourth Largest Lake in Europe|
|Predicting Future Introductions of Nonindigenous Species to the Great Lakes|
|Table of Contents provided by Publisher. All Rights Reserved.|
Series: Series: Environmental Science, Engineering and Technology Ser.
Number Of Pages: 245
Published: 1st March 2011
Dimensions (cm): 22.9 x 15.2
Weight (kg): 0.694