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The HER2 receptor is a 195-kDa transmembrane glycoprotein with tyrosine kinase activity, and belongs in the human epidermal growth factor receptor (HER) family consisting of four members. Moreover, aberrant HER2 protein over-expression has been linked to various human gynaecological adenocarcinomas, including breast, endometrium, ovary and cervix, and has been found to be a poor prognostic factor for survival. This new book presents topical research in the study of HER2, including targeting HER2 with photodynamic therapy; HER2 shedding as a biomarker in breast cancer; development of trastuzumab resistance and targeted nanomedicines conjugated with HER2 antibodies in cancer therapy.
| Preface | |
| Use of Ecological Indices to Detect Changes in Ecosystem Health Following Restoration Efforts in Cootes Paradise Marsh | |
| Changes in Fish Communities of Lake Ontario Coastal Wetlands Before & After Remedial Action Plans | |
| Use of Ecological Indicators to Assess the Quality of Great Lakes Coastal Wetlands | |
| Development of an Inventory of Coastal Wetlands for Eastern Georgian Bay, Lake Huron | |
| Great Lakes: Form & Function, as Exemplified using Data from Lake Vñnern, the Fourth Largest Lake in Europe | |
| Predicting Future Introductions of Nonindigenous Species to the Great Lakes | |
| Index | |
| Table of Contents provided by Publisher. All Rights Reserved. |
ISBN: 9781611226508
ISBN-10: 1611226503
Series: Series: Environmental Science, Engineering and Technology Ser.
Audience:
Professional
Format:
Hardcover
Language:
English
Number Of Pages: 245
Published: 1st March 2011
Dimensions (cm): 22.9 x 15.2
Weight (kg): 0.694
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