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Cord Blood Characteristics

Role in Stem Cell Transplantation

Hardcover

Published: 2nd December 1999
RRP $185.00
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The use of cord blood as a source of haematopoietic stem cell transplantation has steadily increased since the first cord blood transplant 11 years ago. This text reviews the molecular and cellular biology of cord blood, the collection and processing of cord blood units, the clinical potential of ex vivo expansion, and concludes with discussion of cord blood banking and matching, and the ethical and legal issues related to blood cell therapy and transplantation.

Prefacep. vii
Contributorsp. ix
Introduction: Cord blood transplantation - Looking back and to the futurep. 1
Haematopoietic content of cord bloodp. 13
Cord blood T-cell immunobiologyp. 39
Immunobiology of neonatal natural killer (NK) cellsp. 61
Cord blood cytokinesp. 73
In vitro models of graft-versus-host diseasep. 97
Collection and processing of cord blood unitsp. 129
Reducing the risks of disease transmission in cord blood transplantationp. 149
Ex vivo expansion of cord blood cells: The clinical potentialp. 169
Related and unrelated cord blood transplantationp. 205
The significance of HLA matching in cord blood stem cell transplantationp. 217
Ethical, legal and socio-economic issues related to blood cell therapy and transplantationp. 249
Does cord blood transplantation have a future? The immunological perspectivep. 261
Indexp. 269
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9781853177941
ISBN-10: 1853177946
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 296
Published: 2nd December 1999
Dimensions (cm): 24.5 x 19.5  x 2.3
Weight (kg): 0.961