By: John Bienenstock (Editor), Edward J. Goetzl (Editor), M. Blennerhassett (Editor)

Hardcover

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While it may appear that the nervous and immune systems exist as two separate entities, groundbreaking observations have positively identified anatomic connections between elements of the nervous system and cells of adaptive immunity.
Building on this research, Autonomic Neuroimmunology presents a scientific discussion of the current understanding of these vital neuroimmunological interactions and their implications for normal psychology and disease states. Contributors document the cell biological mechanisms for the neuropeptide activation of mast cells, and analyze how one or more adrenergenic and peptidergic messengers modulate immunity. They also explain the pathways by which cholinergic factors may suppress immunological inflammation. The potential implications of organ system-selective neuroimmunology for host defense and diseases are thoroughly discussed for the skin, the intestines, the bladder, and the lungs.
With modern neuroimmunology now firmly established as a scientific discipline, this volume supports this promising science as a pathway to novel diagnostic and therapeutic techniques for diseases of the neural, immune, and endocrine systems.

Preface to the Series - Historical and Conceptual Perspective of the Autonomic Nervous System Book Series	p. vii
Preface	p. xiii
Contributors	p. xv
Sympathetic Innervation of the Immune System and its Role in Modulation of Immune Responses, Immune-Related Diseases Models, and Integrative Medicine	p. 1
Interactions between the Adrenergic and Immune Systems	p. 15
Enteric Neural Reflexes and Secretion	p. 35
The Cholinergic Anti-Inflammatory Pathway	p. 61
Developmental Regulation and Functional Integration by the Vasoactive Intestinal Peptide (VIP) Neuroimmune Mediator	p. 75
An Emerging Role for Calcitonin Gene-Related Peptide in Regulating Immune and Inflammatory Functions	p. 95
Substance P and the Immune System	p. 111
Nerve-Mast Cell Interactions - Partnership in Health and Disease	p. 139
Submandibular Gland Factors and Neuroendocrine Regulation of Inflammation and Immunity	p. 171
Mechanisms by which Lipid Derivatives and Proteinases Signal to Primary Sensory Neurons: Implications for Inflammation and Pain	p. 197
Functional Consequences of Neuroimmune Interactions in the Intestinal Mucosa	p. 215
Infectious Pathogens and the Neuroenteric System	p. 251
Neuroimmune Interactions in the Lung	p. 279
Neuroimmune Control of the Pulmonary Immune Response	p. 295
Regulatory Aspects of Neuroimmunology in the Skin	p. 319
Neuroimmune Connections and Regulation of Function in the Urinary Bladder	p. 345
Index	p. 371
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9780415306584
ISBN-10: 0415306582
Series: Autonomic Nervous Systems
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 418
Published: 13th February 2003
Dimensions (cm): 24.6 x 17.4  x 2.7
Weight (kg): 0.88